Mohamed Sayegh, M.D

     Dr. Mohamed Sayegh received his B.S. in 1980, and his M.D. (honors) in 1984, from the American University of Beirut. He completed his residency in Internal Medicine at the Cleveland Clinic Foundation, Cleveland, Ohio in 1987. His fellowship in nephrology, 1987-90, was completed at Harvard Medical School, Brigham and Women’s Hospital in Boston, MA.  After completing his nephrology fellowship, Dr. Sayegh joined the faculty at Harvard Medical School as Instructor in Medicine in 1990. He currently holds the title of Associate Professor of Medicine at Harvard Medical School, where he is active in both clinical and research activities. His research interest is focused on understanding mechanisms of T cell recognition of alloantigen and T cell costimulatory activation pathways in graft rejection and tolerance in experimental animals and humans.  He also collaborates with investigators at the Surgical Research Laboratory at Harvard Medical School to study non-immunologic mechanisms of chronic graft dysfunction, Center for Neurologic Diseases at the Brigham and Women’s Hospital to study the mechanisms of tolerance in autoimmunity, and the Channing Laboratory to study the role of T cell costimulation in infections and response to vaccines.  In 1999, Dr. Sayegh was appointed as research director of the Nephrology Division at Children’s Hospital in Boston, MA.  In addition to his supervising and teaching of the research fellows in the research laboratory, and teaching responsibilities of the clinical fellows in the renal division, he also serves as co-director of all Harvard CME courses organized by the renal division of the Brigham and Women’s Hospital and Harvard Medical School.  He is widely published, having written over 100 scientific publications dealing with his area of interest. Dr. Sayegh has served as a consultant to, or member of a number of governmental agencies, voluntary health organizations and professional organizations.  He also serves on the Editorial Boards of a number of scientific journals. His contributions have been recognized by such awards as Clinical Scientist Award from the National Kidney Foundation, Mary Jane Kugel Award, Medical Science Research Committee, Juvenile Diabetes Foundation International, Harvard Nominee for King Faisal International Prize in Medicine, and past president of the American Society of  Transplantation.

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